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What is Cialis
Cialis is a PDE5 inhibitor, a drug designed to treat erectile dysfunction (ED). It is a selective inhibitor of cyclic monosphosphate (cGMP)-specific phosphodiesterase type 5. Cialis was approved by the FDA in 2011. It's generic name is Tadalafil and is recommended as an "as needed" medication. It is among the five FDA approved drugs that can be prescribed to treat erectile dysfunction. Cialis begins working within 15-30 minutes after it is taken, and its effects can last up to 36 hours.
How does Cialis work?
Cialis works by increasing blood flow to certain parts of the body. The drug stops an enzyme called phosphodiesterase type 5, which results in more cGMP, increasing the chances for an erection. Cialis relaxes and opens up blood arteries to increase the blood flow.
Unlike other drugs prescribed for erectile dysfunction, Cialis works in combination with sexual stimulation. Nitric oxide is released from nerve endings, which helps in arterial relaxation. Without sexual stimulation, the release of nitric oxide will be hampered and may deter the effects of Cialis. This means there is a low chance of the user experiencing an unwanted erection.
Who should take Cialis?
In addition to those with ED, the drug can also be used to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia - BPH). BPH can cause difficulty in urinating. The drug can help smooth muscles in the bladder and prostate.
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