Pfizer Produces Its Own Generic Viagra
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Pfizer has not owned a patent on Viagra for some time, which is why it is possible to buy it from several manufacturers. When asked what is the generic name for Viagra, and it is correct to answer that all drugs with the active substance sildenafil under different names are generics.
What is generic Viagra?
Generic Viagra (Sildenafil citrate) is a pharmacy drug designated to relieve the symptoms of ED; generic Viagra is taken per os. Sildenafil, the drug’s active component, has no efficacy if the function is normal and cannot be activate in case of the absence of sexually stimulating irritators. The drug is not supposed to be used in such subcategories as females and persons under the age of 18.
Sildenafil citrate as a newly discovered substance was patented by Pfizer in the beginning of 90s and approved by FDA in 1998. During the following decade and a half Viagra was available only in form of drug produced by the original manufacturer, due to the validity of patent. As of recently, sildenafil became available as a considerably cheaper generic Viagra with efficacy and safety identical to those of the original drug.
Mechanism Of Action
The active component of generic Viagra, sildenafil citrate, belongs to the class called scientifically phosphodiesterase type 5 inhibitors with specificity for cyclic GMP), much more effective in promoting penile vasodilation than other selective inhibitors. The effect of sildenafil is completely absent in a denervated penis and is antagonized by substances that inhibit NO synthase. This shows that Viagra is able to enhance a function that must be partially present. It cannot replace a erogenous stimulus, nor can it transform into a stimulus that is not a stimulus. It does not replace the pudenda innervation, but enhances its function if it is lacking. It does not act except in the presence of a vascular system sensitive to NO. It makes no sense to prescribe it against the background of a normal organ function. Not elective in hypogonadism impotence. It is useless in patients with reduced or lack of libido, but not with erection (subjects who have normal and complete erections during the phases of REM sleep, but who do not feel sexual desire: or for psychiatric diseases – typically major depression – or medication – typically certain antidepressants, certain diuretics, etc., or, simply because such individuals do not experiencel any attraction to a certain partner).
The advisability of administering if pharmacologically induced ED is suspected should be cautiously evaluated. In this circumstance, the prescriber of sildenafil must take into consideration: the diagnosis underlying the treatment in progress, the drug’s principles of action and possible interactions of the active substance with other substances administered concomitantly. All these aspects are difficult to evaluate as there is currently no reference literature.
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